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ND News

WE ARE WHAT WE DO · SO SEE WHAT WE ARE DOING

ND PHARMA & BIOTECH GIVES A NEW STEP IN THE UNVEAL OF BRAIN CONNECTION MYSTERIES AND ITS DECIPHERING. (Diffusion Spectrum MRI)

11/29/2012

 
Picture
DIFFUSION SPECTRUM M.R.I. OF ADULT BRAIN SHOWING CONNECTION MAPS IN BETWEEN.
A NEW TECHNIQUE DESIGNED FOR THE COMPREHENSIVE UNDERSTANDING OF HUMAN BRAIN CONNECTIONS WILL BE CO-LAUNCHED WITH PARTNER COMPANIES, WITH AN IMPORTANT IMPACT ON THE STUDY AND THERAPIES DEVELOPMENT OF CERTAIN DISEASES OF THE CENTRAL NERVOUS SYSTEM AND FUTURE TREATMENT OPTIONS.

This project will fill a gap in neuroscience. Scientists understand less about how structure relates to function in the brain than they do for any other organ. Connections between neurons define neuroanatomy, and these thin fiber tracts show up poorly with most imaging technologies. To visualize axons, researchers use a variant of MRI called diffusion tensor imaging, which maps the flow of water through tissues. As fluid moves along versus across axons, the technique allows scientists to see these microscopic projections. A recent advance, diffusion spectrum imaging (DSI), distinguishes intersecting tracts. Crossing fibers cause a problem for dissecting brain structure, because multiple pathways can occupy the same location. With these new techniques, scientists can see things that cannot be seen with any other method. That includes visualizing the three-dimensional fiber architecture of the entire brain, he said.

This project will be an important step in developing connectivity methods that can be used in ALZHEIMER´S DISEASE research. The methods have great potential, and a lot of work is underway to enable optimal measurement stability for time series data.This project exemplifies “big data,” as it will generate about one petabyte, i.e., one quadrillion or 1,000,000,000,000,000 bytes of data, about 2,000 times the size of a typical desktop hard drive.

The high-resolution connectome data generated by partner institutions could have many uses. For example, researchers might identify boundaries between brain regions by looking for changes in connectivity patterns. Using task fMRI data, researchers can ask questions such as, What brain networks co-vary with working memory performance? The findings will identify anatomical pathways relevant to task performance. For example, good two-handed coordination correlates with strong connectivity in a small cluster in the corpus callosum.

While neuroanatomy often looks confusing because of the crossing of multiple fiber pathways, the imaging resolved this into geometric order, showing that cortical fibers form smooth sheets that tend to travel in one of three perpendicular directions, forming a three-dimensional grid. These smooth sheets may reflect concentration gradients from embryological development. Scientists have known for long time, that the cortex starts out as a flat sheet and crumples up during development into the deep convolutions of the adult brain. High-resolution microscopy also reveals that fibers typically make 90 degree turns rather than smooth curves when they need to change direction. This finding illustrates the power of the new machine to provide a more detailed anatomical understanding of the brain. Existing diffusion imaging methods cannot visualize these microscopic turns. Scientists from different sectors became impressed by the fixed patterns revealed by these scans.The architecture of the brain shown is tremendously precise. This should be a huge asset for mapping and looking for changes in disease states.


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  • HELLO WORLD!
  • Trust
  • NOW FEATURING
  • ND Pharma & Biotech
  • About Us
    • Welcome
    • Overview
    • History
  • BUSINESS
    • MLB
    • SALES STRATEGY
    • From Milligrams to Tons
  • PRODUCTS
    • ND Difference
    • GALLERY
    • SAMPLES
    • NUTRACEUTICALS >
      • cardioprime®
    • FOOD-NUTRITION >
      • ACARISIN TM >
        • CROP PROTECTION ACARISIN TM
        • ACARISIN TM EN PROTECCION COSECHAS
        • ACARISIN TM DIFFERENT APPLICATIONS
        • ACARISIN TM RED MITE
      • ACEK 250
      • ACQUALIFE TM/REACT
      • ACQUALIFE TM/ JUICE
      • ACRYLFAST TM
      • ADO(RED) TM
      • ALKIOW TM >
        • ALKIOWORLD
      • Amino-Acids
      • AMINOPROT 1000
      • ANISAKILL TM
      • ArganSoil TM
      • ASPARSOL TM
      • AUGMENTAID TM
      • CALCLOR TM
      • CARRAGéN TM
      • CHIKNSAFE TM
      • COCQWA TM
      • ENVIRUD TM
      • E-SUN TM
      • FERRISTAT TM
      • FOLISOL TM
      • FRUITFRESH TM
      • FULVISOL TM
      • FUNGILAD TM
      • GLAICE
      • GLUCOFEN TM
      • GLYCIMAX TM
      • INOFISH TM
      • INUSOL TM
      • INVERSOL TM
      • KNAMAX TM
      • LACTOBRINE TM
      • LACTOLIFE TM
      • LYSOMAX TM
      • MALTOLAN DRM
      • M.A.R.S. TM
      • MOHOSTOP TM >
        • MOHOSTOP TM/ BAKERY
      • MOLDSTOP TM C/ ADAPTED FORMULA
      • MONKÍ
      • NATICEL CMC 3000
      • NovaDENT
      • PINOLIPOL TM
      • PEPPERSOL TM
      • PRESERFOOD TM >
        • PRESERFOOD TM/ ANTIOX
        • PRESERFOOD TM/ CAVIAR
        • PRESERFOOD TM/ CARNOSOL
        • PRESERFOOD TM/CURED
        • PRESERFOOD TM/ DAIRY & MILK FORMULA
        • PRESERFOOD TM/ FLAVOR
        • PRESERFOOD TM/ MARINE
        • PRESERFOOD TM/ MEAT >
          • PreserFood TM/MEAT-MIX
        • PRESERFOOD TM/ NATURE >
          • PRESERFOOD TM NATURE/ POINT OF SALE
        • PRESERFOOD TM/ NATURE PACK
        • PRESERFOOD TM/ OLIVE
        • PRESERFOOD TM/ SHELLFISH
        • PRESERFOOD TM/ SWEET
        • PRESERFOOD TM/ UOVO
        • PRESERFOOD TM/ WINE
      • PUREMEAT TM >
        • PUREMEAT 100 TM
        • PUREMEAT TM/ BLENDS
      • REDUXALT TM
      • RIBOSOL TM
      • STERILFOOD TM
      • STERILSHIP TM
      • SUCRASOL
      • VEGAFRESH TM
      • VERIKÀ TM
      • VITAFOL TM
      • X-Fresh TM
      • ZEONATUR MED
      • ZOELTAR TM
    • AGRI-BUSINESS >
      • EcoEff(R)
      • FRUITFRESH TM
      • GRUMAX TM
      • STG-Microgene
    • INDUSTRIAL >
      • MBP´s (Mutual Beneficial Partnerships)
      • ON-STOCK PRODUCT´S LIST
      • PHARMACEUTICAL
      • BIOPESTICIDES
      • Fine Chemicals (Brochures from complete list)
    • GLAICE WATER Co.
    • KANGEN
    • NDZymes
  • OUR WORK
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  • SOLUTIONS
    • Strategy
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    • Work
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  • LEGAL
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  • MORE
  • CONTACT
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  • Thanks for Visiting